SCHEMBL1275741

SCHEMBL1275741

c1ccc(NNCC2CO2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CTSD P07339 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTR1A P08908 2/20 0.37
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37
LMNA P02545 1/20 0.37
KCNH3 Q9ULD8 1/20 0.36
TSHR P16473 1/20 0.35
GLA P06280 1/20 0.34
CHRM2 P08172 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175818 0.79 NPC1 (0.56) TDP1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL11132542 0.73 SMN1; SMN2 (0.50) TDP1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL28162974 0.69 ALDH1A1 (0.42) TDP1ALDH1A1SMN1; SMN2TSHR
SCHEMBL8981523 0.69 TAAR1 (0.42) TDP1ALDH1A1NPC1RAB9ASMN1; SMN2
Diphenylmethane SCHEMBL9322142 0.68 CALM1 (0.48) ALDH1A1SMN1; SMN2HTR1AADRA1DADRA1A
SCHEMBL409525 0.68 ALDH1A1 (0.50) TDP1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL19624824 0.68 ALDH1A1 (0.42) TDP1ALDH1A1CTSDNPC1RAB9A
Toluene SCHEMBL10589939 0.68 LMNA (0.44) TDP1ALDH1A1RAB9ASMN1; SMN2HTR1A
SCHEMBL19125641 0.68 DRD2 (0.56) TDP1ALDH1A1MEN1KMT2A
SCHEMBL2592594 0.68 DRD2 (0.56) TDP1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586283-B2 Near-infrared absorbing film compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-11-19 US disclosed
US-20130001484-A1 Near-Infrared Absorbing Film Compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-01-03 US disclosed
US-8293451-B2 Near-infrared absorbing film compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-10-23 US disclosed
US-20110042653-A1 Near-Infrared Absorbing Film Compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-02-24 US disclosed
WO-2011022221-A2 NEAR-INFRARED ABSORBING FILM COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-02-24 WO disclosed