SCHEMBL15935780

SCHEMBL15935780

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(C)c(N=Nc4c(S(=O)(=O)O)cc5cc(Nc6ccc(N)c(S(=O)(=O)O)c6)ccc5c4O)cc3C)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 9/20 0.56
▸ CD40 P25942 1/20 0.48
▸ CD40LG P29965 1/20 0.48
▸ PRMT1 Q99873 2/20 0.45
▸ CARM1 Q86X55 1/20 0.45
▸ SUMO2 P61956 1/20 0.45
▸ SUMO1 P63165 1/20 0.45
▸ SENP7 Q9BQF6 1/20 0.45
▸ SENP3 Q9H4L4 1/20 0.45
▸ SENP2 Q9HC62 1/20 0.45
▸ SENP1 Q9P0U3 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ PHLPP2 Q6ZVD8 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ CTDSP1 Q9GZU7 1/20 0.43
▸ PRMT3 O60678 1/20 0.41
▸ EP300 Q09472 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757652 0.92 ENPP2 (0.61) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL12757650 0.91 ENPP2 (0.60) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL11913411 0.90 ENPP2 (0.68) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL14773624 0.89 ENPP2 (0.60) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL14024915 0.89 ENPP2 (0.65) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL14001674 0.89 ENPP2 (0.45) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL12757656 0.88 ENPP2 (0.68) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL12757648 0.88 ENPP2 (0.68) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL14024916 0.87 ENPP2 (0.62) ENPP2CD40CD40LGPRMT1CARM1
SCHEMBL19958202 0.85 ENPP2 (0.66) ENPP2CD40CD40LGSUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 — — US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 — — US disclosed
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 — — WO disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 — — US disclosed
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