Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760762 | 0.91 | WDR5 (0.39) | WDR5KLKB1 | |
| SCHEMBL12757696 | 0.90 | WDR5 (0.46) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL1495704 | 0.90 | WDR5 (0.44) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL2171975 | 0.87 | P2RX3 (0.48) | WDR5 | |
| SCHEMBL1495673 | 0.87 | WDR5 (0.41) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL12757687 | 0.85 | WDR5 (0.42) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL1495435 | 0.84 | WDR5 (0.42) | WDR5HDAC1KDM1AKLKB1 | |
| SCHEMBL1495418 | 0.83 | WDR5 (0.40) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL1495361 | 0.83 | WDR5 (0.41) | WDR5HDAC1KDM1AKLKB1AKR1C3 | |
| SCHEMBL1495707 | 0.83 | P2RX3 (0.47) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | RENOVIS, INC. | 2015-09-24 | — | — | US | disclosed |
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | RENOVIS, INC. | 2015-09-24 | — | — | US | disclosed |
| US-8946439-B2 | Amide compounds, compositions and uses thereof | EVOTEC AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8946439-B2 | Amide compounds, compositions and uses thereof | EVOTEC AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20110065681-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110065681-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065681-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | IL1B, ADORA2B, AVPR1B | WDR5 1801/4885HDAC1 442/4885KDM1A 2778/4885 |
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | IL1B, ADORA2B, AVPR1B | WDR5 1801/4885HDAC1 442/4885KDM1A 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.