SCHEMBL12759222

SCHEMBL12759222

CCCOCC(N)(COCCC)COCCC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
CES1 P23141 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12759058 0.95 HSD17B10 (0.32) HSD17B10
SCHEMBL10106991 0.90 ALDH1A1 (0.35) HSD17B10
SCHEMBL15375170 0.83 TSHR (0.44) CES1CA1CA2
SCHEMBL469014 0.82 ALDH1A1 (0.37) HSD17B10
SCHEMBL12760550 0.82 ALDH1A1 (0.37) HSD17B10
SCHEMBL12759071 0.81
SCHEMBL19866145 0.80
SCHEMBL13165938 0.79 CES1 (0.53) CES1CA1CA2
SCHEMBL12141358 0.79 ALDH1A1 (0.34)
SCHEMBL12759069 0.79 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340000-A1 FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS HONGENE BIOTECH CORPORATION 2023-10-26 US disclosed
US-11692001-B2 Functionalized n-acetylgalactosamine analogs HONGENE BIOTECH CORPORATION (US) 2023-07-04 US disclosed
US-20150196655-A1 CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2015-07-16 US disclosed
US-7932326-B2 Chelating compounds and immobilized tethered chelators THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2011-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340000-A1 FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS FUT6, CSGALNACT1, GALNT6 HSD17B10 3264/4885CES1 1480/4885CA1 2423/4885
US-11692001-B2 Functionalized n-acetylgalactosamine analogs FUT6, CSGALNACT1, GALNT6 HSD17B10 3264/4885CES1 1480/4885CA1 2423/4885
US-20150196655-A1 CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION RNASE1, IGF2BP1, IGF2BP2 HSD17B10 2672/4885CES1 1325/4885CA1 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.