Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 3/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | CDK9 | P50750 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.62 |
| ▸ | ITGAV | P06756 | 2/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275926 | 0.90 | RAB9A (0.75) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL1659299 | 0.89 | DDX3X (1.00) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11918074 | 0.89 | DDX3X (1.00) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL5852186 | 0.89 | DDX3X (0.70) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL6799221 | 0.88 | RAB9A (0.73) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL10212601 | 0.87 | DDX3X (0.68) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL687547 | 0.86 | RAB9A (0.66) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL3460449 | 0.86 | DDX3X (0.70) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL688197 | 0.86 | DDX3X (0.66) | DDX3XRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL17084259 | 0.86 | RAB9A (0.67) | DDX3XRAB9AKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630512-B2 | Antiinflammatory agents; autoimmune disease | BIOGEN, INC. | 2003-10-07 | — | — | US | claimed |
| US-6624152-B2 | Inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention relates to pharmaceutical formulations comprising these compounds and methods of using them for inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-09-23 | — | — | US | claimed |
| US-20030083267-A1 | Cell adhesion inhibitors | BIOGEN, INC., A MASSACHUSETTS CORPORATION | 2003-05-01 | — | — | US | claimed |
| US-20030018016-A1 | Cell adhesion inhibitors | BIOGEN IDEC MA, INC. | 2003-01-23 | — | — | US | claimed |
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |
| US-6376538-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | BIOGEN, INC. | 2002-04-23 | — | — | US | claimed |
| US-6306840-B1 | ANTISTICKING AGENTS OF OLIGOPEPTIDES | BIOGEN, INC. | 2001-10-23 | — | — | US | claimed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | claimed |
| CN-119993845-A | Method for manufacturing circuit board | 味之素株式会社 | 2025-05-13 | — | — | CN | disclosed |
| EP-3432881-B1 | USE OF DDX3 INHIBITORS AS ANTIPROLIFERATIVE AGENTS | AZIENDA OSPEDALIERA UNIV SENESE (IT) | 2021-11-24 | — | — | EP | disclosed |
| CN-112533967-A | Oil-in-water emulsion of active energy ray-curable resin composition and thermal recording material | 日本化药株式会社 | 2021-03-19 | — | — | CN | disclosed |
| WO-2020039601-A1 | OIL-IN-WATER TYPE EMULSION OF ACTINIC-RAY-CURABLE RESIN COMPOSITION, AND THERMAL RECORDING MATERIAL | 日本化薬株式会社 | 2020-02-27 | — | — | WO | disclosed |
| US-10030138-B2 | High thermal conductivity thermoplastic resin composition with excellent injection moldability | KANEKA CORPORATION (JP) | 2018-07-24 | — | — | US | disclosed |
| EP-1142867-A2 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |
| US-4156675-A | ANTISTATIC PROPERTIES, ELECTROLYTES, SURFACTANTS | NHK SPRING CO., LTD. (JP) | 1979-05-29 | — | — | US | disclosed |
| US-4136079-A | UREA COMPOUND HAVING CARBOXYLATE RADICAL AND METHOD FOR PRODUCING THE SAME | NHK SPRING CO., LTD. (JP) | 1979-01-23 | — | — | US | disclosed |
| US-3936484-A | Production of isocyanates from substituted ureas | ATLANTIC RICHFIELD COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083267-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | DDX3X 3590/4885RAB9A 1779/4885KMT2A 3376/4885 |
| US-20030018016-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | DDX3X 3590/4885RAB9A 1779/4885KMT2A 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.