SCHEMBL1275966

SCHEMBL1275966

Cc1ccc(O)c(/N=N/c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 1/20 1.00
MAPT P10636 9/20 0.66
L3MBTL1 Q9Y468 6/20 0.66
NPC1 O15118 6/20 0.66
RAB9A P51151 6/20 0.66
MAPK1 P28482 5/20 0.66
CASP3 P42574 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
THRB P10828 1/20 0.59
NQO2 P16083 1/20 0.54
TDP1 Q9NUW8 3/20 0.52
MEN1 O00255 7/20 0.51
KMT2A Q03164 7/20 0.51
POLB P06746 3/20 0.51
GAA P10253 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HSP90AA1 P07900 3/20 0.50
MPL P40238 1/20 0.50
CCR6 P51684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275967 1.00 FTO (1.00) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL23511143 0.89 FTO (0.79) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL12565720 0.89 FTO (0.79) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL7913514 0.86 NPC1 (0.80) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL8204503 0.86 NPC1 (0.80) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL15214125 0.85 FTO (0.74) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL11305360 0.85 FTO (0.73) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL11305364 0.85 FTO (0.73) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL9148461 0.84 FTO (0.72) FTOMAPTL3MBTL1NPC1RAB9A
SCHEMBL9148464 0.84 FTO (0.72) FTOMAPTL3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof AJINOMOTO CO., INC. (JP) 2024-07-02 US disclosed
US-11873359-B2 Photocurable composition, three-dimensional molded product, and dental product MITSUI CHEMICALS, INC. (JP) 2024-01-16 US disclosed
US-11873359-B2 Photocurable composition, three-dimensional molded product, and dental product MITSUI CHEMICALS, INC. (JP) 2024-01-16 US disclosed
US-20210300972-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2021-09-30 US disclosed
US-20170175017-A1 METHOD OF MAKING HYDROCARBON LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-06-22 US disclosed
US-9650538-B2 Method for manufacturing micro-structure SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-16 US disclosed
US-9625440-B2 Method of marking hydrocarbon liquids JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-04-18 US disclosed
US-9606435-B2 Method for manufacturing micro-structure and optically patternable sacrificial film-forming composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-28 US disclosed
US-9557664-B2 Electrophotographic photosensitive member, method for manufacturing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-01-31 US disclosed
US-9557664-B2 Electrophotographic photosensitive member, method for manufacturing the same, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-01-31 US disclosed
WO-2011020928-A2 PHOTORESPONSIVE SUNSCREEN COMPOSITION BLUESHIFT PHARMA GMBH (CH) 2011-02-24 WO disclosed
US-7708396-B2 Photochromic phase change inks XEROX CORPORATION (US) 2010-05-04 US disclosed
US-20070211124-A1 PHOTOCHROMIC PHASE CHANGE INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-7022331-B2 Thermochromic/photochromic cosmetic compositions Theisen, Lyle (US) 2006-04-04 US disclosed
US-20020192247-A1 Thermochromic/photochromic cosmetic compositions THEISEN LYLE (US) 2002-12-19 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024549-B2 Compound having affinity substance to soluble protein, cleavable portion and reactive group, or salt thereof SPPL2B, CSTB, SPPL2A FTO 4457/4885MAPT 4288/4885L3MBTL1 2461/4885
US-11873359-B2 Photocurable composition, three-dimensional molded product, and dental product F9, TAS2R9, TAS1R1 FTO 2099/4885MAPT 180/4885L3MBTL1 4569/4885
US-20210300972-A1 COMPOUND HAVING AFFINITY SUBSTANCE TO ANTIBODY, CLEAVABLE PORTION, AND REACTIVE GROUP, OR SALT THEREOF FCGR3B, FCGR2A, QPCTL FTO 4276/4885MAPT 3657/4885L3MBTL1 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.