SCHEMBL8204503

SCHEMBL8204503

Cc1ccc(O)c(N=Nc2cc(C)ccc2O)c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.80
RAB9A P51151 4/20 0.80
FTO Q9C0B1 1/20 0.74
MAPT P10636 11/20 0.65
L3MBTL1 Q9Y468 4/20 0.65
MAPK1 P28482 4/20 0.65
HSP90AA1 P07900 1/20 0.61
CCR6 P51684 1/20 0.61
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
ALDH1A1 P00352 4/20 0.58
GAA P10253 4/20 0.58
POLB P06746 1/20 0.58
THRB P10828 1/20 0.57
KDM4E B2RXH2 5/20 0.57
HTT P42858 5/20 0.57
LMNA P02545 4/20 0.57
TRPA1 O75762 1/20 0.56
TDP1 Q9NUW8 4/20 0.54
TP53 P04637 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913514 1.00 NPC1 (0.80) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL11305364 0.89 FTO (0.73) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL11305360 0.89 FTO (0.73) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL23511143 0.89 FTO (0.79) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL12565720 0.89 FTO (0.79) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL1615338 0.86 NPC1 (0.73) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL1275966 0.86 FTO (1.00) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL1275967 0.86 FTO (1.00) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL29377457 0.86 NPC1 (0.73) NPC1RAB9AFTOMAPTL3MBTL1
SCHEMBL11955367 0.86 NPC1 (0.73) NPC1RAB9AFTOMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
US-4074046-A REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE AMERICAN CYANAMID COMPANY (US) 1978-02-14 US disclosed