SCHEMBL12759666

SCHEMBL12759666

c1ccc2c(c1)c1ccncc1n1ccnc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.37
MAOB P27338 5/20 0.37
ACHE P22303 1/20 0.37
IDO1 P14902 3/20 0.37
KDM4E B2RXH2 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
IKBKB O14920 1/20 0.36
AURKA O14965 1/20 0.36
CHUK O15111 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PIM1 P11309 1/20 0.36
TOP1 P11387 1/20 0.36
GABRA1 P14867 1/20 0.36
HPGD P15428 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12759662 0.87 MAOA (0.44) MAOAMAOBACHEKDM4EPARP1
SCHEMBL29636632 0.84 MAPK8 (0.41) KDM4EALDH1A1SMN1; SMN2DYRK1AMAPT
SCHEMBL840406 0.84 MAPK8 (0.41) KDM4EALDH1A1SMN1; SMN2DYRK1AMAPT
SCHEMBL840252 0.82 MAPK8 (0.40) KDM4EALDH1A1SMN1; SMN2DYRK1AMAPT
SCHEMBL16193834 0.82 MAPK8 (0.40) ALDH1A1SMN1; SMN2DYRK1AMAPTSLC6A2
SCHEMBL16193836 0.82 MAPK8 (0.40) ALDH1A1SMN1; SMN2DYRK1AMAPTSLC6A2
SCHEMBL20561462 0.80 CHUK (0.40) IDO1CHUKGABRA1GABRA5MAPT
SCHEMBL21918445 0.79 PDE2A (0.42) MAOAMAOBACHEIDO1KDM4E
SCHEMBL23948664 0.78 KDM4E (0.42) KDM4EDYRK1AMAPK8
SCHEMBL23948685 0.78 KDM4E (0.42) KDM4EDYRK1AMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-07-13 US disclosed
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues UNITED STATES DEPARTMENT OF ENERGY 2020-04-16 US disclosed
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-10-29 US disclosed
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-10-29 US disclosed
US-9062084-B2 Method of forming metal complex compound, and organic electroluminescence device UDC Ireland (IE) 2015-06-23 US disclosed
US-9062084-B2 Method of forming metal complex compound, and organic electroluminescence device UDC Ireland (IE) 2015-06-23 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 MAOA 812/4885MAOB 1119/4885ACHE 367/4885
US-20150311455-A1 Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device ZFR, PORCN, OR10J3 MAOA 812/4885MAOB 1119/4885ACHE 367/4885
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues IK, HELZ, SUN2 MAOA 302/4885MAOB 1164/4885ACHE 1246/4885
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues IK, HELZ, SUN2 MAOA 302/4885MAOB 1164/4885ACHE 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.