Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636632 | 0.98 | MAPK8 (0.41) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL840406 | 0.98 | MAPK8 (0.41) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16193834 | 0.96 | MAPK8 (0.40) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16193836 | 0.96 | MAPK8 (0.40) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21917657 | 0.87 | HTR3E (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11459997 | 0.84 | ALDH1A1 (0.41) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12759666 | 0.82 | MAOA (0.37) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12759662 | 0.82 | MAOA (0.44) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20367894 | 0.82 | DDB1 (0.36) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12076941 | 0.82 | MAPT (0.41) | MAPK8HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10008678-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-06-26 | — | — | US | disclosed |
| EP-3081617-B1 | BLUE EMITTER WITH HIGH EFFICIENCY BASED ON IMIDAZO [1,2-F] PHENANTHRIDINE IRIDIUM COMPLEXES | UNIVERSAL DISPLAY CORP (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-3081617-A1 | BLUE EMITTER WITH HIGH EFFICIENCY BASED ON IMIDAZO [1,2-F] PHENANTHRIDINE IRIDIUM COMPLEXES | Universal Display Corporation (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-2382281-B1 | BLUE EMITTER WITH HIGH EFFICIENCY BASED ON IMIDAZO [1,2-f] PHENANTHRIDINE IRIDIUM COMPLEXES | UNIVERSAL DISPLAY CORP (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20140319504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2014-10-30 | — | — | US | disclosed |
| US-8815415-B2 | Blue emitter with high efficiency based on imidazo[1,2-f] phenanthridine iridium complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815415-B2 | Blue emitter with high efficiency based on imidazo[1,2-f] phenanthridine iridium complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-26 | — | — | US | disclosed |
| US-8142909-B2 | Blue phosphorescent imidazophenanthridine materials | UNIVERSAL DISPLAY CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100148663-A1 | Blue Emitter with High Efficiency Based on Imidazo[1,2-f] Phenanthridine Iridium Complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100148663-A1 | Blue Emitter with High Efficiency Based on Imidazo[1,2-f] Phenanthridine Iridium Complexes | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2008156879-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20080297033-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | UNIVERSAL DISPLAY CORPORATION | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10008678-B2 | Organic electroluminescent materials and devices | EML4, TYR, EZH2 | MAPK8 2757/4885HTR3E 2382/4885HTR3B 2710/4885 |
| US-20080297033-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | IK, CRY1, MAP1LC3C | MAPK8 3076/4885HTR3E 2249/4885HTR3B 2669/4885 |
| US-20100148663-A1 | Blue Emitter with High Efficiency Based on Imidazo[1,2-f] Phenanthridine Iridium Complexes | IK, CRY2, TYR | MAPK8 2872/4885HTR3E 2391/4885HTR3B 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.