SCHEMBL9050192

SCHEMBL9050192

C=C(c1ccccc1)C(Cl)CCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
LMNA P02545 3/20 0.36
MAPT P10636 3/20 0.36
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
ATM Q13315 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
XBP1 P17861 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
AOC3 Q16853 2/20 0.36
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
PRSS1 P07477 1/20 0.35
CTSG P08311 1/20 0.35
CTRB1 P17538 1/20 0.35
CMA1 P23946 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28985808 0.84 LMNA (0.39) LMNAMAPTCES2CES1ATM
SCHEMBL3728429 0.78 SLC6A2 (0.54) SLC6A2SLC6A3LMNAMAPTCES2
SCHEMBL11112637 0.78 MAOA (0.32) LMNAMAPTCES1ATMSMN1; SMN2
SCHEMBL5034590 0.77 SMN1; SMN2 (0.39) SLC6A2SLC6A3LMNAMAPTCES2
SCHEMBL1276189 0.76 LMNA (0.42) SLC6A2SLC6A3LMNAMAPTATM
SCHEMBL3386407 0.76 SLC6A2 (0.44) SLC6A2SLC6A3LMNAMAPTCES2
SCHEMBL4021295 0.73 LMNA (0.47) LMNAMAPTCES2CES1ATM
SCHEMBL5036785 0.72 PTGS2 (0.42) LMNAMAPTCES2CES1ATM
SCHEMBL11215655 0.71 SMN1; SMN2 (0.47) LMNAMAPTCES2CES1ATM
SCHEMBL10435495 0.70 PPARG (0.40) SLC6A2SLC6A3LMNAMAPTCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491189-A BINDER DISPERSION CONSISTS OF A HALOGENATED COPOLYMER OF 2,3-DIHALO-1,3-BUTADIENE, AROMATIC MONOALKYENE ALKYL HALIDE, UNSATURATED OLEFIN, AND CONTAINS ADDITIVE, PARTLY SAPONIFIED VINYL ACETATE COPOLYMER, AROMATIC POLYNITROSO COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-02-13 US disclosed
EP-0470105-B1 AQUEOUS VULCANIZING ADHESIVE HENKEL KGAA (DE) 1994-07-27 EP disclosed
EP-0345455-B1 Composition for the surface treatment of polymer fibres HENKEL KGAA (DE) 1993-11-03 EP disclosed
US-5118430-A Polar phenoplast of the resol type and a copolymer crosslinkable with resols E. I. DU PONT DE NEMOURS AND COMPANY 1992-06-02 US disclosed
EP-0470105-A1 AQUEOUS VULCANIZING ADHESIVE. HENKEL KGAA (DE) 1992-02-12 EP disclosed
WO-1990012847-A1 AQUEOUS VULCANIZING ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-11-01 WO disclosed
EP-0345455-A2 Composition for the surface treatment of polymer fibres Henkel Kommanditgesellschaft auf Aktien (DE) 1989-12-13 EP disclosed