SCHEMBL12762428

SCHEMBL12762428

COc1c(C)cc(-c2cc(C)c(OC(=O)c3cccc(C(C)=O)c3)c(C)c2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ POLB P06746 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ KMT2A Q03164 6/20 0.40
▸ MEN1 O00255 4/20 0.40
▸ ESR1 P03372 1/20 0.40
▸ ESR2 Q92731 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ NPC1 O15118 4/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ TNFRSF1A P19438 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ CREBBP Q92793 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16573866 0.89 MAPT (0.42) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL12346020 0.88 ESR1 (0.41) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL12762425 0.88 ALDH1A1 (0.40) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL12762419 0.87 KMT2A (0.41) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL139355 0.85 KMT2A (0.39) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL13865060 0.85 ESR1 (0.39) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL13657589 0.85 TSHR (0.47) MAPTALDH1A1POLBKMT2AMEN1
SCHEMBL142008 0.83 MAPT (0.38) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL13865058 0.83 KMT2A (0.41) MAPTALDH1A1POLBGFERKMT2A
SCHEMBL14007584 0.83 ESR1 (0.39) MAPTALDH1A1POLBGFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 — — US disclosed
US-20170060008-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20160154326-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-02 — — US disclosed
US-20160139556-A1 PROCESS CARTRIDGE AND IMAGE-FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-05-19 — — US disclosed
US-9235144-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-01-12 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
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