SCHEMBL12762425

SCHEMBL12762425

COc1c(C)cc(Cc2cc(C)c(OC(=O)c3cccc(C(C)=O)c3)c(C)c2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.40
▸ MAPT P10636 3/20 0.40
▸ POLB P06746 1/20 0.40
▸ GFER P55789 1/20 0.40
▸ NPC1 O15118 2/20 0.39
▸ MAOB P27338 3/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ CREBBP Q92793 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ TSHR P16473 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ LOXL2 Q9Y4K0 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ CYP4F2 P78329 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139355 0.97 KMT2A (0.39) ALDH1A1MAPTPOLBGFERNPC1
SCHEMBL13865058 0.95 KMT2A (0.41) ALDH1A1MAPTPOLBGFERNPC1
SCHEMBL13018407 0.88 LOXL2 (0.46) ALDH1A1MAPTPOLBNPC1MEN1
SCHEMBL12762428 0.88 MAPT (0.43) ALDH1A1MAPTPOLBGFERNPC1
SCHEMBL15164083 0.88 KMT2A (0.46) ALDH1A1MAPTPOLBMAOBKMT2A
SCHEMBL12376954 0.88 KMT2A (0.46) ALDH1A1MAPTPOLBMAOBKMT2A
SCHEMBL14125309 0.86 KMT2A (0.45) ALDH1A1MAPTPOLBMEN1KMT2A
SCHEMBL16573866 0.85 MAPT (0.42) ALDH1A1MAPTPOLBGFERNPC1
SCHEMBL12346020 0.84 ESR1 (0.41) ALDH1A1MAPTPOLBGFERNPC1
SCHEMBL13864971 0.84 LOXL2 (0.49) ALDH1A1MAPTPOLBNPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 — — US disclosed
US-20170060008-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20160202621-A1 TONER AND IMAGE FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-07-14 — — US disclosed
US-20160154326-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-02 — — US disclosed
US-20160139556-A1 PROCESS CARTRIDGE AND IMAGE-FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-05-19 — — US disclosed
US-9274442-B2 Electrophotographic image forming apparatus having charge transport layer with matrix-domain structure and charging member having concavity and protrusion CANON KABUSHIKI KAISHA (JP) 2016-03-01 — — US disclosed
US-9235144-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-01-12 — — US disclosed
US-20150277244-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-10-01 — — US disclosed
US-9091912-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-07-28 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
Send feedback