Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696105 | 0.81 | FURIN (0.40) | FURINKDM4EALDH1A1PKML3MBTL1 | |
| SCHEMBL12767469 | 0.81 | TP53BP1 (0.46) | FURINKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17018685 | 0.71 | PKM (0.43) | FURINKDM4EALDH1A1PKML3MBTL1 | |
| SCHEMBL12377935 | 0.71 | GAA (0.46) | FURINKDM4EALDH1A1PKML3MBTL1 | |
| SCHEMBL12735803 | 0.69 | KCNN4 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL12377927 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3043951 | 0.65 | PARP1 (0.52) | FURINALDH1A1KMT2ALMNAPARP1 | |
| SCHEMBL21249304 | 0.64 | LMNA (0.58) | ALDH1A1KMT2ASMN1; SMN2HDAC6HDAC8 | |
| SCHEMBL13701766 | 0.62 | S100B (0.60) | ALDH1A1PKML3MBTL1MEN1KMT2A | |
| SCHEMBL3043953 | 0.61 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642008-B2 | Molecular probe for imaging of pancreatic islets and use of the same | KYOTO UNIVERSITY (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20110059483-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059483-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, SSTR1, SSTR3 | FURIN 3250/4885KDM4E 3805/4885ALDH1A1 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.