SCHEMBL12769375

SCHEMBL12769375

CCOC(=O)C1CCC(c2ccc(-c3ccc(-c4ccc(C(C)C)cc4)s3)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ GAA P10253 2/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ FFAR1 O14842 1/20 0.37
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14231794 0.91 NPC1 (0.44) SMN1; SMN2ALDH1A1MEN1KMT2AGAA
SCHEMBL12947709 0.88 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E
SCHEMBL14145322 0.86 L3MBTL1 (0.47) SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E
SCHEMBL14207667 0.82 ACACB (0.48) SMN1; SMN2ALDH1A1MEN1KMT2AGAA
SCHEMBL22852265 0.76 LMNA (0.46) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL14207647 0.76 ESR2 (0.45) SMN1; SMN2ALDH1A1KDM4EFFAR1NPC1
SCHEMBL13186435 0.76 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1MEN1KMT2AGAA
SCHEMBL12769364 0.75 NPC1 (0.49) ALDH1A1KMT2AGAAFFAR1NPC1
SCHEMBL27595975 0.75 NPC1 (0.41) ALDH1A1KMT2AGAAFFAR1NPC1
SCHEMBL16477198 0.73 MEN1 (0.44) ALDH1A1MEN1KMT2AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7898625-B2 Liquid crystal device having a pair of electrodes with a vertical alignment film in which the chiral pitch length to gap ratio (P/G) is 0.06 to less than 1.0 FUJIFILM CORPORATION (JP) 2011-03-01 — — US disclosed
US-7898625-B2 Liquid crystal device having a pair of electrodes with a vertical alignment film in which the chiral pitch length to gap ratio (P/G) is 0.06 to less than 1.0 FUJIFILM CORPORATION (JP) 2011-03-01 — — US disclosed
US-7871539-B2 Liquid crystal composition, liquid crystal element, reflective display material, light-controlling material, and method of preparing liquid crystal composition FUJIFILM CORPORATION (JP) 2011-01-18 — — US disclosed
US-7820071-B2 Light modulating material and light modulating method FUJIFILM CORPORATION (JP) 2010-10-26 — — US disclosed
US-7780870-B2 Liquid crystal composition, liquid crystal element, and siloxane polymer FUJIFILM CORPORATION (JP) 2010-08-24 — — US disclosed
US-7763883-B2 Image display device FUJIFILM CORPORATION (JP) 2010-07-27 — — US disclosed
US-7713437-B2 Liquid crystal composition, liquid crystal element, reflective display material, and light-controlling material FUJIFILM CORPORATION (JP) 2010-05-11 — — US disclosed
US-20100092784-A1 OPTICAL FILM, AND GLASS FUJIFILM CORPORATION (JP) 2010-04-15 — — US disclosed
US-20100039595-A1 LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2010-02-18 — — US disclosed
US-20100039595-A1 LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2010-02-18 — — US disclosed
US-7316829-B2 Liquid crystal composition and display device FUJIFILM CORPORATION (JP) 2008-01-08 — — US disclosed
US-20070278449-A1 Liquid crystal composition, liquid crystal element, reflective display material, and light-controlling material FUJIFILM CORPORATION 2007-12-06 — — US disclosed
US-20070218216-A1 Light modulating material FUJIFILM CORPORATION 2007-09-20 — — US disclosed
US-7270857-B2 Liquid crystal composition and liquid crystal element FUJIFILM CORPORATION (JP) 2007-09-18 — — US disclosed
US-20070131903-A1 Dichroic dye and a low molecular weight gelling agent, high display performance FUJIFILM CORPORATION 2007-06-14 — — US disclosed
US-7220466-B2 Liquid crystal composition and liquid crystal device FUJIFILM CORPORATION (JP) 2007-05-22 — — US disclosed
US-7220466-B2 Liquid crystal composition and liquid crystal device FUJIFILM CORPORATION (JP) 2007-05-22 — — US disclosed
US-20070071911-A1 pair of electrodes of which at least one is a transparent electrode and a liquid crystal layer between; liquid crystal layer contains at least two compositions of dual frequency addressable smectic liquid crystal compositions having different threshold voltages; a guest-host type liquid crystal element FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-20070007492-A1 Liquid crystal composition, liquid crystal element, and cross-linked siloxane polymer FUJI PHOTO FILM CO., LTD. (JP) 2007-01-11 — — US disclosed
US-20070003735-A1 Display device FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 — — US disclosed
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