Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 14/20 | 0.81 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.69 |
| ▸ | TUBB | P07437 | 9/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.69 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.69 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.69 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.68 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9906591 | 1.00 | TUBB1 (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13813234 | 0.95 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14514240 | 0.89 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5848534 | 0.87 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5848055 | 0.87 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31237302 | 0.87 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12855359 | 0.87 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13763739 | 0.86 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14649649 | 0.86 | TUBB1 (0.68) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12593810 | 0.86 | TUBB1 (0.68) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897820-B2 | Process for preparing erianin | ZHE JIANG CELL BIOMEDICAL RESEARCH CO., LTD. (CN) | 2011-03-01 | — | — | US | disclosed |
| US-7557096-B2 | Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof | Arizona Board of Regents, a body corporate of the State of Arizona, acting for an on behalf of the Arizona State University (US) | 2009-07-07 | — | — | US | disclosed |
| US-20090018369-A1 | PROCESS FOR PREPARING ERIANIN | ZHEJIANG TIANHUANG MEDICINAL PLANT PHARMACEUTICAL CO., LTD. (CN) | 2009-01-15 | — | — | US | disclosed |
| US-7279466-B2 | Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof | ARIZONA BOARD OF REGENTS (US) | 2007-10-09 | — | — | US | disclosed |
| US-20070203217-A1 | SUBSTITUTED STILBENES AND THEIR REACTIONS | UNIVERSITEIT UTRECHT UU HOLDING B.V. (NL) | 2007-08-30 | — | — | US | disclosed |
| US-7220784-B2 | Substituted stilbenes and their reactions | CANCER RESEARCH VENTURES LIMITED (GB) | 2007-05-22 | — | — | US | disclosed |
| US-20070073077-A1 | Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof | Arizona Board of Regents, a body corporate of the state of Arizona, acting for and on behalf of | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073077-A1 | Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof | COASY, TMPRSS4, CDK4 | TUBB1 2109/4885TUBB4A 532/4885TUBB 2244/4885 |
| US-20070203217-A1 | SUBSTITUTED STILBENES AND THEIR REACTIONS | CASP4, ATG4B, CTSB | TUBB1 1146/4885TUBB4A 568/4885TUBB 1056/4885 |
| US-20090018369-A1 | PROCESS FOR PREPARING ERIANIN | ERLIN1, ERLIN2, EI24 | TUBB1 2267/4885TUBB4A 541/4885TUBB 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.