SCHEMBL1277161

SCHEMBL1277161

CCCCCCn1[c]ncc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.44
TLR8 Q9NR97 2/20 0.38
NPC1 O15118 7/20 0.35
RAB9A P51151 7/20 0.35
HTT P42858 6/20 0.35
MAPK1 P28482 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
POLB P06746 3/20 0.35
LMNA P02545 3/20 0.35
GALR3 O60755 2/20 0.35
ATM Q13315 2/20 0.35
HSP90AA1 P07900 2/20 0.35
MAPT P10636 2/20 0.35
APOBEC3A P31941 2/20 0.35
APOBEC3G Q9HC16 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RAD52 P43351 1/20 0.35
PAX8 Q06710 1/20 0.35
NR2F2 P24468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27544368 1.00 TBXAS1 (0.44) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL1277116 0.98 TBXAS1 (0.41) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL1277074 0.92
SCHEMBL9481880 0.69 TBXAS1 (0.41) TBXAS1NPC1RAB9AHTTMAPK1
SCHEMBL6114927 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL11440961 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL6114991 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL6114640 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL11438392 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT
SCHEMBL6114716 0.67 TBXAS1 (0.47) TBXAS1TLR8NPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2450985-B1 ELECTRODE FOR SECONDARY BATTERY, SLURRY FOR SECONDARY BATTERY ELECTRODE, AND SECONDARY BATTERY ZEON CORP (JP) 2017-09-27 EP disclosed
US-9098001-B2 Surface-modified metal oxide powder and process for producing same NIPPON AEROSIL CO., LTD. (JP) 2015-08-04 US disclosed
US-8877376-B2 Electrode for secondary battery, slurry for secondary battery electrode, and secondary battery ZEON CORPORATION (JP) 2014-11-04 US disclosed
US-8841024-B2 2014-09-23 US disclosed
EP-2450985-A1 ELECTRODE FOR SECONDARY BATTERY, SLURRY FOR SECONDARY BATTERY ELECTRODE, AND SECONDARY BATTERY Zeon Corporation (JP) 2012-05-09 EP disclosed
US-20120107690-A1 ELECTRODE FOR SECONDARY BATTERY, SLURRY FOR SECONDARY BATTERY ELECTRODE, AND SECONDARY BATTERY ZEON CORPORATION (JP) 2012-05-03 US disclosed
US-20120085978-A1 SURFACE-MODIFIED METAL OXIDE POWDER AND PROCESS FOR PRODUCING SAME NIPPON AEROSIL CO., LTD. (JP) 2012-04-12 US disclosed
EP-2236566-A1 Water-insoluble colorant dispersion Fujifilm Corporation (JP) 2010-10-06 EP disclosed
US-20100247878-A1 WATER-INSOLUBLE COLORANT DISPERSION FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
CN-100384825-C Benzheterocyclic derivatives OTSUKA PHARMA CO LTD (JP) 2008-04-30 CN disclosed
US-5670526-A ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-09-23 US disclosed
CN-1158129-A Novel benzimidazole derivatives having CGMP-phosphodisterase inhibiting activity OTSUKA PHARMA CO LTD (JP) 1997-08-27 CN disclosed
CN-1150799-A Benzoheterocyclic derivatives OTSUKA PHARMA CO LTD (JP) 1997-05-28 CN disclosed
EP-0468470-B1 Benzimidazoles, medicaments containing them and process for their preparation THOMAE GMBH DR K (DE) 1997-04-16 EP disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1997003070-A1 NOVEL BENZIMIDAZOLE DERIVATIVES HAVING CGMP-PHOSPHODISTERASE INHIBITING ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-01-30 WO disclosed
US-5587393-A ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION DR. KARL THOMAE GMBH (DE) 1996-12-24 US disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed
US-5385925-A Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them DR. KARL THOMAE GMBH (DE) 1995-01-31 US disclosed
EP-0468470-A1 Benzimidazoles, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120085978-A1 SURFACE-MODIFIED METAL OXIDE POWDER AND PROCESS FOR PRODUCING SAME TFRC, ITGA4, FEM1B TBXAS1 4252/4885TLR8 4418/4885NPC1 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.