SCHEMBL12773263

SCHEMBL12773263

Cc1ccc(Pc2ccccc2OCc2ccccc2)c(C(C)O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
MAPK1 P28482 2/20 0.42
MAPT P10636 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 6/20 0.40
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SGMS2 Q8NHU3 1/20 0.40
LIPE Q05469 1/20 0.40
CCR5 P51681 1/20 0.39
HPGD P15428 3/20 0.39
HTT P42858 2/20 0.39
TSHR P16473 1/20 0.39
PTGER1 P34995 2/20 0.39
PTGER4 P35408 2/20 0.39
PTGER3 P43115 2/20 0.39
PTGER2 P43116 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12773252 0.94 CCR5 (0.43) TDP1MAPK1MAPTL3MBTL1KDM4E
SCHEMBL12773289 0.89 CCR5 (0.43) TDP1MAPK1MAPTL3MBTL1KDM4E
SCHEMBL12773239 0.87 LIPE (0.45) TDP1MAPK1MAPTL3MBTL1KDM4E
SCHEMBL12773316 0.87 HPGD (0.41) ALDH1A1HPGDHTTMRGPRX4RAB9A
SCHEMBL12773276 0.85 HTR1A (0.39) TDP1MAPK1MAPTL3MBTL1ALDH1A1
SCHEMBL12773220 0.84 L3MBTL1 (0.33) TDP1MAPTL3MBTL1KDM4ELMNA
SCHEMBL12773304 0.83 GLRA1 (0.39) MAPK1ALDH1A1LMNACCR5HPGD
SCHEMBL12773168 0.80 PTGER1 (0.46) TDP1MAPK1MAPTL3MBTL1ALDH1A1
SCHEMBL12773249 0.80 MRGPRX4 (0.38) MAPK1ALDH1A1LMNAHPGDHTT
SCHEMBL12773725 0.80 MRGPRX4 (0.47) TDP1MAPK1MAPTL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 TDP1 4437/4885MAPK1 1478/4885MAPT 2719/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 TDP1 4437/4885MAPK1 1478/4885MAPT 2719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.