Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 9/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777898 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HSD17B10GPR3AHRHPGD | |
| SCHEMBL21356683 | 0.75 | AHR (0.45) | ALDH1A1HSD17B10GPR3AHRHPGD | |
| SCHEMBL12778111 | 0.75 | DAO (0.53) | ALDH1A1HSD17B10AHRCYP1A2CYP2C19 | |
| SCHEMBL29812052 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HSD17B10GPR3AHRHPGD | |
| SCHEMBL20005057 | 0.75 | DAO (0.53) | ALDH1A1HSD17B10GPR3AHRKDM4E | |
| SCHEMBL12778107 | 0.75 | IMPDH2 (0.47) | ALDH1A1HSD17B10GPR3AHRCYP1A2 | |
| SCHEMBL31070422 | 0.75 | AHR (0.45) | ALDH1A1HSD17B10GPR3AHRHPGD | |
| SCHEMBL12777897 | 0.75 | KIF11 (0.40) | ALDH1A1AHRCYP1A2CYP2C19TNKS2 | |
| SCHEMBL12778104 | 0.71 | DYRK1A (0.41) | HTTSMN1; SMN2IMPDH2IMPDH1 | |
| SCHEMBL12778105 | 0.71 | KMT2A (0.53) | KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |