Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814976 | 0.83 | KMT2A (0.39) | LMNAPTBP1SMN1; SMN2IDO1KMT2A | |
| SCHEMBL6814979 | 0.83 | KMT2A (0.39) | LMNAPTBP1SMN1; SMN2IDO1KMT2A | |
| SCHEMBL12779138 | 0.80 | ADRA1A (0.41) | LMNAKMT2AL3MBTL1ADRA1A | |
| SCHEMBL12779147 | 0.77 | HTT (0.40) | KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL20831352 | 0.76 | IDO1 (0.40) | IDO1KMT2AATMHCRTR1HCRTR2 | |
| SCHEMBL12779219 | 0.75 | CCR5 (0.33) | LMNASMN1; SMN2KMT2AL3MBTL1MAPT | |
| SCHEMBL12778438 | 0.74 | NR3C2 (0.38) | SMN1; SMN2NR3C2ADRA1A | |
| SCHEMBL27485011 | 0.73 | IDO1 (0.39) | IDO1KMT2AATMCYP3A4ESR1 | |
| SCHEMBL12779144 | 0.73 | ALDH1A1 (0.38) | LMNASMN1; SMN2KMT2AL3MBTL1MAPT | |
| SCHEMBL30172263 | 0.73 | TSHR (0.52) | LMNASMN1; SMN2KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |