SCHEMBL1278010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1277858	0.86	RAB9A (0.52)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL1278087	0.85	XDH (0.63)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL1277966	0.85	XDH (0.74)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL1277485	0.85	XDH (0.63)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL2768879	0.84	FBP1 (0.64)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL3416258	0.83	FBP1 (0.49)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL3421501	0.82	MAPT (0.52)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL3032700	0.82	XDH (0.70)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL3727035	0.82	XDH (0.49)	XDHFBP1NPC1MAPTRAB9A
	SCHEMBL1278007	0.81	XDH (0.68)	XDHFBP1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.