Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | LTA4H | P09960 | 5/20 | 0.82 |
| ▸ | ATP4A | P20648 | 2/20 | 0.60 |
| ▸ | ATP4B | P51164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8355367 | 0.98 | RAB9A (0.96) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL5455207 | 0.95 | RAB9A (0.90) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29654110 | 0.92 | MAPT (0.84) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL5461678 | 0.91 | NPC1 (0.82) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1771825 | 0.84 | ALDH1A1 (0.79) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23610361 | 0.82 | ALDH1A1 (0.83) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13394699 | 0.82 | MAPT (0.73) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5328219 | 0.81 | ALDH1A1 (0.69) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28931077 | 0.81 | NPC1 (0.69) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1180215 | 0.81 | MAPT (0.84) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049686-A1 | S-TRIAZINE DERIVATIVES AND THEIR USE AS UV FILTERS | L'OREAL (FR) | 2001-07-12 | — | — | WO | claimed |
| EP-0006368-B1 | 4-PHENYL-THIAZOLYL-2-OXAMATE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF ASTHMA | PIERRE FABRE S.A. (FR) | 1981-11-18 | — | — | EP | claimed |
| CN-120247900-A | Phenyl thiazole amine pyrimidine derivative, and preparation method and application thereof | 南京市鸿舜医药科技有限公司 | 2025-07-04 | — | — | CN | disclosed |
| US-20250051296-A1 | MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2025-02-13 | — | — | US | disclosed |
| US-20240327427-A1 | NEW COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2024-10-03 | — | — | US | disclosed |
| US-12103917-B2 | Modulators of myocyte lipid accumulation and insulin resistance and methods of use thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-10-01 | — | — | US | disclosed |
| CN-118344304-A | Ibuprofen derivative and preparation method and application thereof | 华南农业大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-3799871-B1 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOTOTIC BAX | DANA FARBER CANCER INST INC (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-116854683-A | Coumarin thiazole derivative and preparation method and application thereof | 中北大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-113861186-B | Isoxazole-based substituted benzamide derivative and application of anti-prostate cancer drug | 浙江师范大学 | 2023-08-25 | — | — | CN | disclosed |
| US-11584742-B2 | Substituted aminothiazoles as inhibitors of nucleases | MASARYKOVA UNIVERZITA (CZ) | 2023-02-21 | — | — | US | disclosed |
| EP-0161442-A2 | Thiazolyl ureas, process for their preparation and their use to combat undesired plant growth | BASF Aktiengesellschaft (DE) | 1985-11-21 | — | — | EP | disclosed |
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0044442-A1 | N-(4-Phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |
| US-4246271-A | ANTIALLERGENS | PIERRE FABRE, S.A. (FR) | 1981-01-20 | — | — | US | disclosed |
| US-4225610-A | TREATMENT OF RHEUMATOID ARTHRITIS | PIERRE FABRE, S.A. (FR) | 1980-09-30 | — | — | US | disclosed |
| US-4207233-A | Azo dyes containing a thiazole component | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584742-B2 | Substituted aminothiazoles as inhibitors of nucleases | RNASEH1, DNASE1, FEN1 | RAB9A 2879/4885NPC1 3091/4885MAPT 706/4885 |
| US-20250051296-A1 | MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF | MYC, MYCBP, MLYCD | RAB9A 3766/4885NPC1 187/4885MAPT 2121/4885 |
| US-20240327427-A1 | NEW COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | PSEN2, PSEN1, CHAT | RAB9A 1895/4885NPC1 146/4885MAPT 13/4885 |
| US-12103917-B2 | Modulators of myocyte lipid accumulation and insulin resistance and methods of use thereof | MYC, MYCBP, MLYCD | RAB9A 3766/4885NPC1 187/4885MAPT 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.