SCHEMBL12786282

SCHEMBL12786282

COC(=O)C(C)CSCCOP(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MVD P53602 1/20 0.38
LPAR3 Q9UBY5 4/20 0.34
LPAR1 Q92633 2/20 0.34
LPAR2 Q9HBW0 2/20 0.34
TPI1 P60174 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
ENPP2 Q13822 4/20 0.31
PGD P52209 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14418411 0.81 PGD (0.40) MVDLPAR3LPAR1LPAR2TPI1
SCHEMBL17640896 0.78 DGKA (0.35)
SCHEMBL3461124 0.78 SMN1; SMN2 (0.41)
SCHEMBL26873542 0.76 MVD (0.31) MVD
SCHEMBL16688133 0.74 PGK1 (0.45) LPAR3LPAR1LPAR2PGK1PGK2
SCHEMBL12769059 0.74 CA1 (0.43)
SCHEMBL284761 0.73 SMN1; SMN2 (0.41)
SCHEMBL28832815 0.72 FOLH1 (0.33)
SCHEMBL9014430 0.72 ZDHHC7 (0.43)
SCHEMBL10633453 0.72 METAP2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897712-B2 Organic-inorganic hybrid composition, method for producing the same, molding and optical component FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-20110043932-A1 LENS DEVICE FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed
US-20110026109-A1 OPTICAL LENS, OPTICAL SYSTEM UNIT AND IMAGING APPARATUS FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20100296181-A1 PLASTIC LENS FUJIFILM CORPORATION (JP) 2010-11-25 US disclosed
US-20090017280-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, METHOD FOR PRODUCING THE SAME, MOLDING AND OPTICAL COMPONENT FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed