Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21689751 | 1.00 | CES2 (0.41) | CES2CES1TSHRMAPK1ALOX15 | |
| SCHEMBL18789917 | 0.88 | ALDH5A1 (0.37) | MAPK1ALOX15CYP3A4CYP1A2MAPT | |
| SCHEMBL20848294 | 0.79 | PTGS1 (0.36) | CES2CES1TSHRMAPK1ALOX15 | |
| SCHEMBL7500354 | 0.79 | ALDH1A1 (0.43) | CES2CES1ATMMAPTHPGD | |
| SCHEMBL21880243 | 0.79 | ALDH1A1 (0.43) | CES2CES1ATMMAPTHPGD | |
| SCHEMBL7500360 | 0.79 | ALDH1A1 (0.43) | CES2CES1ATMMAPTHPGD | |
| SCHEMBL9682609 | 0.77 | CES2 (0.46) | CES2CES1TSHRMAPK1ALOX15 | |
| SCHEMBL19301051 | 0.77 | CES2 (0.41) | CES2CES1CA1CA2CYP1A2 | |
| SCHEMBL19071788 | 0.77 | CES2 (0.46) | CES2CES1TSHRMAPK1ALOX15 | |
| SCHEMBL9682602 | 0.77 | CES2 (0.46) | CES2CES1TSHRMAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765961-B2 | Near infrared fluorescent imaging agent | FUJIFILM CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20110054181-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | FUJIFILM CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054181-A1 | NEAR INFRARED FLUORESCENT IMAGING AGENT | MSR1, RXFP1, IK | CES2 649/4885CES1 992/4885TSHR 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.