SCHEMBL21689751

SCHEMBL21689751

C=C/C(=C\C)c1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
ALOX15 P16050 1/20 0.39
CYP3A4 P08684 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 3/20 0.37
CYP2A6 P11509 1/20 0.36
PTGS1 P23219 1/20 0.36
BCL2L1 Q07817 1/20 0.36
SRD5A2 P31213 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786451 1.00 CES2 (0.41) CES2CES1TSHRMAPK1ALOX15
SCHEMBL18789917 0.88 ALDH5A1 (0.37) MAPK1ALOX15CYP3A4CYP1A2MAPT
SCHEMBL20848294 0.79 PTGS1 (0.36) CES2CES1TSHRMAPK1ALOX15
SCHEMBL7500354 0.79 ALDH1A1 (0.43) CES2CES1ATMMAPTHPGD
SCHEMBL21880243 0.79 ALDH1A1 (0.43) CES2CES1ATMMAPTHPGD
SCHEMBL7500360 0.79 ALDH1A1 (0.43) CES2CES1ATMMAPTHPGD
SCHEMBL9682609 0.77 CES2 (0.46) CES2CES1TSHRMAPK1ALOX15
SCHEMBL19301051 0.77 CES2 (0.41) CES2CES1CA1CA2CYP1A2
SCHEMBL19071788 0.77 CES2 (0.46) CES2CES1TSHRMAPK1ALOX15
SCHEMBL9682602 0.77 CES2 (0.46) CES2CES1TSHRMAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020027589-A1 NOVEL POLYMER AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2020-02-06 WO disclosed