Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.41 |
| ▸ | USP2 | O75604 | 9/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788928 | 0.89 | CYP1A2 (0.43) | THRBTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12788918 | 0.83 | HTT (0.40) | CYP3A4LMNAMEN1KMT2AHSD17B10 | |
| SCHEMBL12788030 | 0.82 | TP53 (0.60) | TP53CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12811336 | 0.80 | KDM4E (0.41) | THRBMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL12340562 | 0.80 | THRB (0.48) | THRBTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12788275 | 0.80 | GRM4 (0.36) | — | |
| SCHEMBL2181171 | 0.80 | THRB (0.41) | THRBTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12788277 | 0.79 | OPRM1 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL12788280 | 0.79 | THRB (0.41) | THRBLMNAMAPK1MAPTNPSR1 | |
| SCHEMBL12788320 | 0.79 | LMNA (0.35) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | CBR3, CBR1, AKR1C4 | THRB 2649/4885TP53 3757/4885CYP1A2 97/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | THRB 2451/4885TP53 1287/4885CYP1A2 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.