Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | CBS | P35520 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | P4HB | P07237 | 3/20 | 0.55 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18670353 | 0.92 | CYP3A4 (0.69) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL1278982 | 0.92 | CYP3A4 (0.69) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL9992609 | 0.92 | CYP3A4 (0.69) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL1287866 | 0.92 | CYP3A4 (0.69) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL181120 | 0.89 | KDM4E (0.65) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL2510457 | 0.82 | NQO2 (0.72) | CYP3A4CA12CA4CA7EPHX2 | |
| SCHEMBL17938761 | 0.78 | CYP3A4 (0.61) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL2002343 | 0.78 | CA12 (0.65) | CYP3A4CA12CA4CA7TYR | |
| SCHEMBL2007120 | 0.78 | NQO2 (0.65) | CYP3A4CA12CA4CA7EPHX2 | |
| SCHEMBL7601750 | 0.78 | KDM4E (0.73) | CYP3A4CA12CA4CA7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | claimed |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | US | claimed |
| US-9351492-B2 | Anti-biofilm compositions and methods for using | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2014-09-18 | — | — | US | disclosed |
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | CYP3A4 3665/4885CA12 2383/4885CA4 1273/4885 |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | CYP3A4 3665/4885CA12 2383/4885CA4 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.