SCHEMBL12791104

SCHEMBL12791104

CCCCCCCCCCCCCN(C(C)C)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.50
THRB P10828 2/20 0.44
TSHR P16473 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
THRA P10827 1/20 0.42
SPHK1 Q9NYA1 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
S1PR2 O95136 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
S1PR5 Q9H228 1/20 0.39
GBA1 P04062 1/20 0.37
PLA2G1B P04054 1/20 0.37
PLA2G2A P14555 1/20 0.37
GGPS1 O95749 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20142522 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL4260574 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL627232 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL12791152 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL2322366 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL9398013 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL12791220 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL20746956 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL21126455 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A
SCHEMBL11262421 1.00 DNM1 (0.50) DNM1THRBTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3538575-B1 HIGH CIS-1,4 BLOCK COPOLYMERS OF POLYBUTADIENE AND POLYISOPRENE BRIDGESTONE CORP (JP) 2024-03-13 EP disclosed
US-11884767-B2 High cis-1,4 block copolymers of polybutadiene and polyisoprene BRIDGESTONE CORPORATION (JP) 2024-01-30 US disclosed
US-11696953-B2 Poly(beta-amino esters) and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-11 US disclosed
US-20220119573-A1 HIGH CIS-1,4 BLOCK COPOLYMERS OF POLYBUTADIENE AND POLYISOPRENE BRIDGESTONE CORPORATION (JP) 2022-04-21 US disclosed
US-11230622-B2 High cis-1,4 block copolymers of polybutadiene and polyisoprene BRIDGESTONE CORPORATION (JP) 2022-01-25 US disclosed
US-20210388196-A1 GENE DELIVERY CARRIER MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-12-16 US disclosed
EP-3538575-A1 HIGH CIS-1,4 BLOCK COPOLYMERS OF POLYBUTADIENE AND POLYISOPRENE Bridgestone Corporation (JP) 2019-09-18 EP disclosed
CN-110139882-A High cis-1, 4 block copolymers of polybutadiene and polyisoprene 株式会社普利司通 2019-08-16 CN disclosed
WO-2018089635-A1 HIGH CIS-1,4 BLOCK COPOLYMERS OF POLYBUTADIENE AND POLYISOPRENE BRIDGESTONE CORPORATION (JP) 2018-05-17 WO disclosed
US-20160009657-A1 AMINE-CONTAINING LIPIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-14 US disclosed
US-9006487-B2 Amine-containing lipids and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-04-14 US disclosed
US-20110052673-A1 THERAPEUTIC COMPOSITIONS SHIRE HUMAN GENETIC THERAPIES, INC. 2011-03-03 US disclosed
US-20110009641-A1 Amine-containing lipids and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110052673-A1 THERAPEUTIC COMPOSITIONS PHOSPHO1, SGMS1, APOB DNM1 1206/4885THRB 3156/4885TSHR 2608/4885
US-20110009641-A1 Amine-containing lipids and uses thereof PHOSPHO1, CHMP4B, SGMS1 DNM1 946/4885THRB 4746/4885TSHR 4001/4885
US-20210388196-A1 GENE DELIVERY CARRIER PAICS, PBDC1, BCAT1 DNM1 4619/4885THRB 2797/4885TSHR 3794/4885
US-11696953-B2 Poly(beta-amino esters) and uses thereof BCAT1, BCAT2, SNRPE DNM1 2479/4885THRB 1842/4885TSHR 4387/4885
US-20160009657-A1 AMINE-CONTAINING LIPIDS AND USES THEREOF PHOSPHO1, CHMP4B, SGMS1 DNM1 946/4885THRB 4746/4885TSHR 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.