Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059074 | 1.00 | SLC1A1 (0.57) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| SCHEMBL2389104 | 1.00 | SLC1A1 (0.57) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL5487502 | 0.98 | SLC1A1 (0.56) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL29886043 | 0.98 | SLC1A1 (0.56) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL5487507 | 0.98 | SLC1A1 (0.56) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL5926216 | 0.90 | SLC1A1 (0.48) | SLC1A1LTA4HPPARA | |
| SCHEMBL4449200 | 0.87 | SLC1A1 (0.46) | SLC1A1LTA4HTACR1 | |
| SCHEMBL589861 | 0.87 | SLC1A1 (0.46) | SLC1A1LTA4HTACR1 | |
| SCHEMBL7419155 | 0.87 | SLC1A1 (0.60) | SLC1A1LTA4HTACR1ALDH1A1CA1 | |
| SCHEMBL7419152 | 0.87 | SLC1A1 (0.60) | SLC1A1LTA4HTACR1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222646-A | KRAS G12C inhibitors and uses thereof | 苏州赞荣医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| US-9247759-B2 | Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |
| CN-104130247-A | Human T2R bitter taste receptors and the use thereof | SENOMYX INC | 2014-11-05 | — | — | CN | disclosed |
| CN-101828111-B | Human T2R bitter taste receptor and uses thereof | SENOMYX INC | 2014-07-23 | — | — | CN | disclosed |
| US-20130345222-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS THAT RESPOND TO BITTER COMPOUNDS THAT ELICIT THE BITTER TASTE IN COMPOSITIONS, AND THE USE THEREOF IN ASSAYS TO IDENTIFY COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITIONS AND USE THEREOF | FIRMENICH INCORPORATED | 2013-12-26 | — | — | US | disclosed |
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | SENOMYX, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8445692-B2 | Compounds that inhibit (block) bitter taste in composition and use thereof | SENOMYX INC. (US) | 2013-05-21 | — | — | US | disclosed |
| EP-2487169-A1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | Senomyx Inc. (US) | 2012-08-15 | — | — | EP | disclosed |
| EP-1000085-A1 | TREATMENT OF INSULIN RESISTANCE WITH GROWTH HORMONE SECRETAGOGUES | Pfizer Products Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| CN-1206422-A | Growth-hormone secretagogues | PFIZER (US) | 1999-01-27 | — | — | CN | disclosed |
| WO-1998058949-A1 | TREATMENT OF INSULIN RESISTANCE WITH GROWTH HORMONE SECRETAGOGUES | PFIZER PRODUCTS INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| EP-0869968-A1 | GROWTH-HORMONE SECRETAGOGUES | PFIZER INC. (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1997024369-A1 | GROWTH-HORMONE SECRETAGOGUES | PFIZER INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |
| EP-0466200-A1 | Aminocarboxylic acids and derivatives thereof | NYCOMED IMAGING AS (NO) | 1992-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | SLC1A1 2448/4885LTA4H 2845/4885TACR1 3553/4885 |
| US-20130183252-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME | TAS2R50, TAS2R1, TAS2R5 | SLC1A1 1096/4885LTA4H 1575/4885TACR1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.