Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12795337 | 0.83 | MAPK1 (0.36) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL17029699 | 0.80 | ALDH1A1 (0.36) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL12034185 | 0.68 | ALDH1A1 (0.39) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL24504568 | 0.68 | PTGS2 (0.39) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL24504697 | 0.66 | KMT2A (0.49) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL12034125 | 0.66 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL24504356 | 0.66 | KMT2A (0.33) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL16601906 | 0.65 | APAF1 (0.39) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL18631945 | 0.65 | PTGS1 (0.43) | TSHRALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL12034181 | 0.65 | TDP2 (0.41) | TSHRALDH1A1LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7896931-B2 | Hair dye composition | KAO CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7896931-B2 | Hair dye composition | KAO CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20100146716-A1 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100146716-A1 | HAIR DYE COMPOSITION | KAO CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100146716-A1 | HAIR DYE COMPOSITION | ARSA, H1-4, H1-0 | TSHR 675/4885ALDH1A1 585/4885LMNA 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.