SCHEMBL12798583

SCHEMBL12798583

Cc1cc(N)cc(C(=O)Oc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.54
MAPT P10636 9/20 0.49
ALOX5 P09917 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP3A4 P08684 2/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
TBXA2R P21731 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
ADRA1A P35348 1/20 0.49
KDR P35968 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
PARP10 Q53GL7 1/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 3/20 0.45
TMPRSS15 P98073 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8421936 0.92 NSD2 (0.62) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL4356752 0.88 NSD2 (0.62) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL2633411 0.88 NSD2 (0.62) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL2814309 0.88 NSD2 (0.62) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL27551844 0.83 NSD2 (0.57) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL12122677 0.82 MAPT (0.56) MAPTCYP3A4LMNAKMT2AMEN1
SCHEMBL16518614 0.82 THRB (0.43) MAPTSMN1; SMN2KMT2AMEN1PRSS1
SCHEMBL10033583 0.81 MAPT (0.62) MAPTALOX5SMN1; SMN2CYP3A4LMNA
SCHEMBL29067609 0.79 MAPT (0.56) NSD2MAPTALOX5SMN1; SMN2CYP3A4
SCHEMBL20348502 0.79 PRSS1 (0.50) NSD2MAPTALOX5SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7901745-B2 3,4-dicarboxy-1,2,3,4-tetrahydro-6-t-butyl-1-naphthalene-succinic dianhydride and liquid crystal aligning agent comprising polyimide resin prepared from the dianhydride CHEIL INDUSTRIES INC. (KR) 2011-03-08 US disclosed
US-20090299014-A1 3,4-Dicarboxy-1,2,3,4-tetrahydro-6-t-butyl-1-naphthalene-succinic Dianhydride and Liquid Crystal Aligning Agent Comprising Polyimide Resin Prepared from the Dianhydride CHEIL INDUSTRIES INC. (KR) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299014-A1 3,4-Dicarboxy-1,2,3,4-tetrahydro-6-t-butyl-1-naphthalene-succinic Dianhydride and Liquid Crystal Aligning Agent Comprising Polyimide Resin Prepared from the Dianhydride SYNGR2, RCC1, DYNC1LI1 NSD2 1594/4885MAPT 338/4885ALOX5 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.