SCHEMBL1279945

SCHEMBL1279945

N#Cc1ccccc1OCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.63
GAA P10253 1/20 0.63
PTGDR2 Q9Y5Y4 6/20 0.62
MAPK1 P28482 1/20 0.61
ALDH1A1 P00352 5/20 0.60
HPGD P15428 2/20 0.60
TSHR P16473 1/20 0.60
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
TP53 P04637 2/20 0.58
POLB P06746 1/20 0.56
GLA P06280 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KDM4E B2RXH2 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NOTUM Q6P988 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1384171 0.85 NPC1 (0.74) SMN1; SMN2GAAPTGDR2MAPK1ALDH1A1
SCHEMBL13664958 0.84 SMN1; SMN2 (0.64) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL3553806 0.84 SMN1; SMN2 (0.61) SMN1; SMN2GAAPTGDR2MAPK1ALDH1A1
SCHEMBL2221490 0.84 SMN1; SMN2 (0.70) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL4841450 0.83 LMNA (0.58) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL3943926 0.81 ALDH1A1 (0.52) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL7218028 0.81 ALDH1A1 (0.76) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL13744249 0.81 NOTUM (0.74) SMN1; SMN2GAAMAPK1ALDH1A1HPGD
SCHEMBL340762 0.80 L3MBTL1 (0.80) SMN1; SMN2PTGDR2ALDH1A1HPGDPOLB
SCHEMBL29682135 0.80 L3MBTL1 (0.80) SMN1; SMN2PTGDR2ALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008522811-A 2008-07-03 JP claimed
JP-2007532569-A 2007-11-15 JP claimed
EP-1843841-A1 CATALYST AND METHOD FOR CONVERTING LOW MOLECULAR WEIGHT PARAFFINIC HYDROCARBONS INTO ALKENES HRD Corp (US) 2007-10-17 EP claimed
EP-1735260-A2 PURIFICATION OF CARBOXYLIC ACIDS BY COMPLEXATION WITH SELECTIVE SOLVENTS GTC Technology, Inc (US) 2006-12-27 EP claimed
WO-2006088470-A2 PURIFICATION OF CARBOXYLIC ACIDS BY COMPLEXATION WITH SELECTIVE SOLVENTS GTC TECHNOLOGY INC. (US) 2006-08-24 WO claimed
US-20060135838-A1 Catalyst and method for converting low molecular weight paraffinic hydrocarbons into alkenes HRD CORP. 2006-06-22 US claimed
WO-2006063230-A1 CATALYST AND METHOD FOR CONVERTING LOW MOLECULAR WEIGHT PARAFFINIC HYDROCARBONS INTO ALKENES HRD CORP. (US) 2006-06-15 WO claimed
US-20050228195-A1 Purification of carboxylic acids by complexation with selective solvents GTC TECHNOLOGY, INC. 2005-10-13 US claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 US claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 WO claimed
US-4831114-A Polymerization of carbon monoxide and olefin with acid catalyst SHELL OIL COMPANY (US) 1989-05-16 US claimed
WO-2026090602-A1 PIGMENTED RESIN AND CATALYST COMPOSITIONS MATERIA, INC. (US) 2026-04-30 WO disclosed
EP-3110862-B1 ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS ExxonMobil Product Solutions Company (US) 2026-04-01 EP disclosed
EP-4683900-A2 ROMP AND THERMAL INSULATION COMPOSITIONS AND MATERIALS AND USE THEREOF Materia, Inc. (US) 2026-01-28 EP disclosed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
EP-0123412-B1 METHOD FOR MANUFACTURE OF DIPHENYLMETHANE DIISOCYANATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-07-09 EP disclosed
US-4552974-A Process for producing diphenylmethane dicarbamates ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-11-12 US disclosed
US-4547322-A Method for manufacture of diphenylmethane diisocyanates ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-10-15 US disclosed
EP-0123412-A1 Method for manufacture of diphenylmethane diisocyanates Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B SMN1; SMN2 1015/4885GAA 1233/4885PTGDR2 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.