Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095070 | 0.80 | KCNH2 (0.44) | TSHRLMNAALDH1A1CETPTP53 | |
| SCHEMBL12802951 | 0.79 | CYP1A2 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL12802835 | 0.79 | CYP1A2 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL12802444 | 0.79 | CYP1A2 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL12802675 | 0.79 | CYP1A2 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL9836712 | 0.79 | BCHE (0.49) | TSHRLMNACETPMAPK1EPHX2 | |
| SCHEMBL27363608 | 0.79 | TSHR (0.43) | TSHRLMNAALDH1A1CETPCYP3A4 | |
| SCHEMBL8366080 | 0.79 | ALDH1A1 (0.44) | TSHRLMNAALDH1A1CETPTP53 | |
| SCHEMBL2368925 | 0.79 | ALDH1A1 (0.44) | TSHRLMNAALDH1A1CETPTP53 | |
| SCHEMBL10770087 | 0.78 | LTA4H (0.44) | TSHRLMNAALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146056-A | Modular compositions for scavenging soluble biomolecules and methods related thereto | 纳米提克斯有限责任公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-113993519-A | Degradation agent for cyclin dependent kinase 12(CDK12) and use thereof | 达纳-法伯癌症研究公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-3898613-A1 | ANTICANCER COMPOUNDS | Pharma Mar S.A. (ES) | 2021-10-27 | — | — | EP | disclosed |
| CN-111825733-A | Macrolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2020-10-27 | — | — | CN | disclosed |
| WO-2020127194-A1 | ANTICANCER COMPOUNDS | PHARMA MAR, S.A. (ES) | 2020-06-25 | — | — | WO | disclosed |
| WO-2014170295-A1 | COMPOUNDS POTENTIATING THE ACTIVITY OF ANTIFUNGAL DRUGS | FUNDACIÓN MEDINA. CENTRO DE EXCELENCIA EN INVESTIGACIÓN DE MEDICAMENTOS INNOVADORES EN ANDALUCÍA (ES) | 2014-10-23 | — | — | WO | disclosed |
| WO-2010149688-A2 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2010-12-29 | — | — | WO | disclosed |
| EP-2231695-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009077401-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |