SCHEMBL12802471

SCHEMBL12802471

O=C([N]O)N1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2677860 0.81 ALDH1A1 (0.48)
SCHEMBL8951223 0.81 ALDH1A1 (0.48)
SCHEMBL103468 0.79 ALDH1A1 (0.52)
SCHEMBL12367675 0.79 ALDH1A1 (0.52)
SCHEMBL10791 0.79 ALDH1A1 (0.52)
SCHEMBL967286 0.77
SCHEMBL8035901 0.75 ALDH1A1 (0.48)
SCHEMBL7932103 0.75 ALDH1A1 (0.48)
SCHEMBL965723 0.75 ALDH1A1 (0.48)
SCHEMBL12489264 0.75 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150216867-A1 COMPOUNDS FOR USE IN GASTRIC COMPLICATION NOVARTIS AG (CH) 2015-08-06 US claimed
EP-2900237-A1 COMPOUNDS FOR USE IN GASTRIC COMPLICATION Novartis AG (CH) 2015-08-05 EP claimed
EP-2694513-B1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2015-01-07 EP claimed
US-8748435-B2 Pyrazolo pyrimidine derivatives NOVARTIS AG (CH) 2014-06-10 US claimed
EP-2694513-A1 PYRAZOLO PYRIMIDINE DERIVATIVES Novartis AG (CH) 2014-02-12 EP claimed
US-20120252778-A1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2012-10-04 US claimed
WO-2012131633-A1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2012-10-04 WO claimed
US-20150216867-A1 COMPOUNDS FOR USE IN GASTRIC COMPLICATION NOVARTIS AG (CH) 2015-08-06 US disclosed
EP-2900237-A1 COMPOUNDS FOR USE IN GASTRIC COMPLICATION Novartis AG (CH) 2015-08-05 EP disclosed
EP-2694513-B1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2015-01-07 EP disclosed
US-8748435-B2 Pyrazolo pyrimidine derivatives NOVARTIS AG (CH) 2014-06-10 US disclosed
EP-2694513-A1 PYRAZOLO PYRIMIDINE DERIVATIVES Novartis AG (CH) 2014-02-12 EP disclosed
WO-2012131633-A1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2012-10-04 WO disclosed
US-20120252778-A1 PYRAZOLO PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2012-10-04 US disclosed