Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385132 | 0.90 | MAPT (0.41) | HPGDALDH1A1SMN1; SMN2HTTPTGS1 | |
| SCHEMBL157545 | 0.87 | PTGS1 (0.41) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL913292 | 0.86 | SMN1; SMN2 (0.38) | HPGDALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL5961226 | 0.86 | PTGS1 (0.46) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL4526904 | 0.83 | GSK3A (0.43) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL20463167 | 0.81 | KMT2A (0.35) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL18122756 | 0.81 | SMN1; SMN2 (0.38) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL24916692 | 0.80 | ALDH1A1 (0.34) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL17915513 | 0.80 | PTGS1 (0.36) | HPGDALDH1A1CYP1A2CYP2C19BLM | |
| SCHEMBL14473389 | 0.80 | ALDH1A1 (0.34) | HPGDALDH1A1CYP1A2CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604383-B1 | PRODUCTION METHOD OF POLYOXYETHYLENE DERIVATIVE HAVING PLURALITY OF HYDROXYL GROUPS AT TERMINAL | NOF CORP (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-10947343-B2 | Production method of polyoxyethylene derivative having plurality of hydroxyl groups at terminal | NOF CORPORATION (JP) | 2021-03-16 | — | — | US | disclosed |
| CN-107573498-B | Polyoxyethylene derivative having plural hydroxyl groups at terminal | 日油株式会社 | 2020-04-24 | — | — | CN | disclosed |
| US-20200079903-A1 | PRODUCTION METHOD OF POLYOXYETHYLENE DERIVATIVE HAVING PLURALITY OF HYDROXYL GROUPS AT TERMINAL | NOF CORPORATION (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3604383-A1 | METHOD FOR PRODUCING POLYOXYETHYLENE DERIVATIVE HAVING HYDROXY GROUPS AT TERMINAL | NOF Corporation (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-8785660-B2 | Polyoxyalkylene-modified lipid and method for producing the same | NOF CORPORATION (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20120253053-A1 | POLYOXYALKYLENE-MODIFIED LIPID AND METHOD FOR PRODUCING THE SAME | NOF CORPORATION (JP) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079903-A1 | PRODUCTION METHOD OF POLYOXYETHYLENE DERIVATIVE HAVING PLURALITY OF HYDROXYL GROUPS AT TERMINAL | ADH1A, ADH1C, LOX | HPGD 320/4885ALDH1A1 10/4885CYP1A2 98/4885 |
| US-10947343-B2 | Production method of polyoxyethylene derivative having plurality of hydroxyl groups at terminal | ADH1A, ADH1C, LOX | HPGD 320/4885ALDH1A1 10/4885CYP1A2 98/4885 |
| US-20120253053-A1 | POLYOXYALKYLENE-MODIFIED LIPID AND METHOD FOR PRODUCING THE SAME | SGMS1, LIPA, SGMS2 | HPGD 2215/4885ALDH1A1 244/4885CYP1A2 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.