Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715197 | 0.86 | ALOX5 (0.44) | ALOX5PTGS2L3MBTL1KDM4EIDO1 | |
| SCHEMBL31395428 | 0.86 | ALOX5 (0.44) | ALOX5PTGS2L3MBTL1KDM4EIDO1 | |
| SCHEMBL17525382 | 0.83 | CA1 (0.50) | L3MBTL1KDM4EIDO1MAPTHPGD | |
| SCHEMBL38657634 | 0.81 | GABRA1 (0.50) | L3MBTL1MAPTTAAR1GABRA1GABRB2 | |
| SCHEMBL19545861 | 0.81 | ALOX5 (0.49) | ALOX5PTGS2L3MBTL1KDM4EIDO1 | |
| SCHEMBL1547302 | 0.77 | CA1 (0.52) | ALOX5PTGS2L3MBTL1KDM4EIDO1 | |
| SCHEMBL172225 | 0.76 | HTR2A (0.46) | ALOX5PTGS2L3MBTL1KDM4EIDO1 | |
| SCHEMBL9046757 | 0.75 | PTGS2 (0.44) | ALOX5PTGS2L3MBTL1KDM4EMAPT | |
| SCHEMBL1044930 | 0.74 | CA1 (0.50) | L3MBTL1KDM4EMAPTHPGDCA12 | |
| SCHEMBL17939 | 0.74 | IDO1 (0.59) | L3MBTL1KDM4EIDO1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308854-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Sanofi-Aventis (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2305651-A1 | 2,3,6-trisubstituted-4-pyrimidone derivatives | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |