Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715197 | 0.86 | ALOX5 (0.44) | ALOX5PTGS2PPARATAAR1KDM4E | |
| SCHEMBL31395428 | 0.86 | ALOX5 (0.44) | ALOX5PTGS2PPARATAAR1KDM4E | |
| SCHEMBL8564056 | 0.86 | CA1 (0.48) | ALOX5PTGS2PPARATAAR1ELANE | |
| SCHEMBL9176631 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2PPARATAAR1ELANE | |
| SCHEMBL13964519 | 0.85 | PTGS2 (0.49) | ALOX5PTGS2PPARATAAR1ELANE | |
| Formaldehyde SCHEMBL27470199 | 0.84 | ALOX5 (0.43) | ALOX5PTGS2PPARATAAR1ELANE | |
| SCHEMBL9046757 | 0.82 | PTGS2 (0.44) | ALOX5PTGS2PPARATAAR1KDM4E | |
| SCHEMBL5348354 | 0.82 | SLC6A4 (0.47) | ALOX5PTGS2TAAR1 | |
| SCHEMBL597268 | 0.81 | GABRA1 (0.50) | TAAR1KDM4EHPGD | |
| SCHEMBL12806358 | 0.81 | ALOX5 (0.41) | ALOX5PTGS2PPARATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340093-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2021-11-04 | — | — | US | disclosed |
| US-20190248725-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2019-08-15 | — | — | US | disclosed |
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248725-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | PTGIS, TFPI, TREH | ALOX5 72/4885PTGS2 76/4885PPARA 1854/4885 |
| US-20170313643-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | PTGIS, CYP2C19, CYP2F1 | ALOX5 1172/4885PTGS2 85/4885PPARA 1975/4885 |
| US-20210340093-A1 | PROCESS FOR THE PREPARATION OF TREPROSTINIL | PTGIS, TFPI, TREH | ALOX5 72/4885PTGS2 76/4885PPARA 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.