Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13137645 | 0.79 | SMN1; SMN2 (0.49) | LMNACYP3A4CHRM2HTR1AADRA2A | |
| SCHEMBL13911202 | 0.79 | SMN1; SMN2 (0.49) | LMNACYP3A4CHRM2HTR1AADRA2A | |
| SCHEMBL9661856 | 0.78 | HTR1A (0.70) | TP53LMNACYP3A4CHRM2HTR1A | |
| SCHEMBL13137652 | 0.78 | ALDH1A1 (0.57) | LMNACYP3A4HTR1ASLC6A2SLC6A4 | |
| SCHEMBL2668990 | 0.74 | TP53 (0.45) | TP53BCHEACHELMNASLC6A4 | |
| SCHEMBL2669158 | 0.74 | TP53 (0.45) | TP53BCHEACHELMNASLC6A4 | |
| SCHEMBL13137646 | 0.74 | CA1 (0.53) | TP53ACHELMNACYP1A2HPGD | |
| SCHEMBL13137650 | 0.73 | ALDH1A1 (0.51) | LMNACYP3A4CHRM2HTR1AADRA2A | |
| SCHEMBL8443448 | 0.73 | HTR1A (0.48) | LMNACYP3A4CHRM2HTR1AADRA2A | |
| SCHEMBL13137649 | 0.73 | ESR1 (0.47) | LMNACYP3A4CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933354-B1 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-03-30 | — | — | EP | disclosed |