Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975423 | 0.89 | HTR1A (0.46) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL12849016 | 0.83 | ADRB2 (0.46) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL12849094 | 0.83 | ADRB2 (0.46) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL13074266 | 0.83 | ADRB2 (0.46) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL172641 | 0.82 | HTR1A (0.54) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL31579895 | 0.82 | HTR1A (0.47) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL18687596 | 0.82 | TAAR1 (0.47) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL13137645 | 0.82 | SMN1; SMN2 (0.49) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL13911202 | 0.82 | SMN1; SMN2 (0.49) | HTR1AHTR7HTR6CYP3A4CHRM2 | |
| SCHEMBL13137652 | 0.81 | ALDH1A1 (0.57) | HTR1AHTR6CYP3A4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933354-B1 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-03-30 | — | — | EP | disclosed |
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| CN-1096781-A | The therapeutical agent that contains 1-(aralkyl-aminoalkyl) imidazolium compounds | BOOTS CO PLC (GB) | 1994-12-28 | — | — | CN | disclosed |