Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813364 | 0.87 | ALDH1A1 (0.34) | RXRACYP1A2RARBRARARARG | |
| SCHEMBL12813412 | 0.86 | SLC6A2 (0.35) | RXRACYP1A2 | |
| SCHEMBL12813191 | 0.84 | KMT2A (0.33) | RXRARXRBRXRGCYP1A2 | |
| SCHEMBL12813356 | 0.83 | TSHR (0.41) | — | |
| SCHEMBL12813156 | 0.82 | HPGD (0.35) | RXRACYP1A2L3MBTL1RARBRARA | |
| SCHEMBL12813285 | 0.81 | GAA (0.38) | RXRARXRBRXRGCYP1A2 | |
| SCHEMBL16499157 | 0.81 | RARB (0.34) | RXRACYP1A2L3MBTL1RARBRARA | |
| SCHEMBL12813371 | 0.81 | CETP (0.35) | — | |
| SCHEMBL12813187 | 0.81 | SLC6A2 (0.42) | L3MBTL1 | |
| SCHEMBL12813698 | 0.80 | RXRA (0.33) | RXRACYP1A2RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |