Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813364 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP1A2RXRA | |
| SCHEMBL12813412 | 0.86 | SLC6A2 (0.35) | CYP1A2RXRAAOC3HSD11B1SLC6A2 | |
| SCHEMBL12813348 | 0.84 | RXRA (0.38) | CYP1A2RXRARXRBRXRG | |
| SCHEMBL12813371 | 0.84 | CETP (0.35) | HSD11B1 | |
| SCHEMBL12813382 | 0.84 | HSD11B1 (0.34) | CYP1A2RXRAHSD11B1 | |
| SCHEMBL12813356 | 0.83 | TSHR (0.41) | KMT2ASLC6A2 | |
| SCHEMBL12813156 | 0.82 | HPGD (0.35) | ATMCYP1A2RXRA | |
| SCHEMBL16499157 | 0.81 | RARB (0.34) | ALDH1A1CYP1A2RXRAHSD11B1 | |
| SCHEMBL12813419 | 0.81 | SLC6A4 (0.39) | ALDH1A1HSD11B1SLC6A2 | |
| SCHEMBL12813503 | 0.81 | SLC6A4 (0.36) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |