Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813364 | 0.84 | ALDH1A1 (0.34) | RARBRARARARGRXRAALDH1A1 | |
| SCHEMBL12813412 | 0.82 | SLC6A2 (0.35) | HSD11B1RXRABRD4CYP1A2 | |
| SCHEMBL12813191 | 0.81 | KMT2A (0.33) | HSD11B1RXRAALDH1A1CYP1A2 | |
| SCHEMBL12813348 | 0.81 | RXRA (0.38) | RARBRARARARGRXRAL3MBTL1 | |
| SCHEMBL16499126 | 0.80 | CYP11B1 (0.36) | ARCYP11B2CYP11B1 | |
| SCHEMBL12813156 | 0.79 | HPGD (0.35) | RARBRARARARGRXRAL3MBTL1 | |
| SCHEMBL12813371 | 0.78 | CETP (0.35) | HSD11B1CYP11B2CYP11B1TOP2ATOP2B | |
| SCHEMBL12813698 | 0.77 | RXRA (0.33) | RARBRARARARGRXRACYP1A2 | |
| SCHEMBL12813382 | 0.75 | HSD11B1 (0.34) | RARBHSD11B1RXRACYP11B2CYP11B1 | |
| SCHEMBL12813419 | 0.75 | SLC6A4 (0.39) | HSD11B1ALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |