SCHEMBL128139

SCHEMBL128139

CNc1cc(O)cc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
BACE1 P56817 1/20 0.50
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
APP P05067 3/20 0.41
CA12 O43570 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA1 P00915 2/20 0.39
CA7 P43166 2/20 0.39
NQO2 P16083 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3226291 0.84 ALDH1A1 (0.57) LMNABACE1ALDH1A1CYP3A4HSD17B10
SCHEMBL5514489 0.82 CA12 (0.55) LMNABACE1ALDH1A1CYP3A4HSD17B10
SCHEMBL15934252 0.82 HCAR1 (0.40) LMNABACE1ALDH1A1CYP3A4HSD17B10
SCHEMBL27782432 0.78 CYP3A4 (0.46) BACE1ALDH1A1CYP3A4HSD17B10TP53
SCHEMBL15934251 0.78 ALDH1A1 (0.39) LMNAALDH1A1CYP3A4HSD17B10TP53
SCHEMBL15934236 0.78 GABRA1 (0.62) LMNAALDH1A1CYP3A4HSD17B10TP53
SCHEMBL15934244 0.78 GABRA1 (0.38) LMNAALDH1A1CYP3A4HSD17B10TP53
SCHEMBL3234059 0.78 ALDH1A1 (0.41) LMNAALDH1A1CYP3A4HSD17B10TP53
SCHEMBL13223483 0.77 MAPT (0.47) LMNAALDH1A1GABRA1GABRB2
SCHEMBL10932391 0.77 CA12 (0.60) LMNAALDH1A1HSD17B10TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1789015-B1 METHOD FOR STYLISHLY CHANGING THE COLOR OF KERATINIC FIBERS HENKEL AG & CO KGAA (DE) 2014-04-23 EP claimed
EP-1286646-B1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KGAA (DE) 2006-05-10 EP claimed
WO-2026098867-A1 OXIDATIVE HAIR BRIGHTENING BY MEANS OF PERSULFATE, DICARBOXYLIC ACID, AND CITRULLINE HENKEL AG & CO. KGAA (DE) 2026-05-15 WO disclosed
WO-2025119816-A1 BLEACHING AGENTS CONTAINING VANILLIN ADDITIVE HENKEL AG & CO. KGAA (DE) 2025-06-12 WO disclosed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US disclosed
EP-4223278-A2 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES Henkel AG & Co. KGaA (DE) 2023-08-09 EP disclosed
CN-112469389-B Amine-based reaction products as functional additives 汉高股份有限及两合公司 2023-06-20 CN disclosed
EP-3826607-B1 AMINE-BASED REACTION PRODUCTS AS FUNCTIONAL ADDITIVES HENKEL AG & CO KGAA (DE) 2023-05-24 EP disclosed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US disclosed
EP-3998059-A9 MILD PREPARATIONS AS CLEANING OR CARE COMPOSITIONS FOR REMOVING CARBOHYDRATES OR STAINS Perfect Ideas GmbH (CH) 2022-09-28 EP disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN disclosed
WO-2001002492-A1 NOVEL DYES AND COLORANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-11 WO disclosed
WO-2001000152-A1 NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLORANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-04 WO disclosed
WO-1999066889-A1 NEW COUPLING COMPONENTS FOR OXIDATION HAIR COLOURING PRODUCTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-12-29 WO disclosed
EP-0278907-B1 CYCLOHEXANE DIONES CIBA-GEIGY AG (CH) 1991-05-29 EP disclosed
US-4994087-A Oxidation dyes producing red shades HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-02-19 US disclosed
US-4872902-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1989-10-10 US disclosed
EP-0278907-A1 Cyclohexane diones CIBA-GEIGY AG (CH) 1988-08-17 EP disclosed
US-4213758-A Oxidation hair dyes based upon tetraaminopyrimidine developers and couplers therefor HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1980-07-22 US disclosed
US-4213758-A Oxidation hair dyes based upon tetraaminopyrimidine developers and couplers therefor HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1980-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO LMNA 2896/4885BACE1 2096/4885ALDH1A1 111/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO LMNA 2896/4885BACE1 2096/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.