SCHEMBL12815852

Cc1cc(C)cc(-c2cc(-c3cc(C)cc(C)c3)cc([Si](Cl)(c3cc(-c4cc(C)cc(C)c4)cc(-c4cc(C)cc(C)c4)c3)c3cc(-c4cc(C)cc(C)c4)cc(-c4cc(C)cc(C)c4)c3)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	RXRA	P19793	1/20	0.34

▸	RXRB	P28702	1/20	0.34

▸	ALDH1A1	P00352	2/20	0.33

▸	TSHR	P16473	1/20	0.33

▸	NOTUM	Q6P988	1/20	0.31

▸	TYMP	P19971	1/20	0.31

▸	FTO	Q9C0B1	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1314841	0.84	ALDH1A1 (0.40)	ALDH1A1TSHRNOTUM
SCHEMBL15411165	0.83	MAPT (0.41)	RXRARXRBALDH1A1FTO
SCHEMBL15410546	0.83	MAPT (0.41)	RXRARXRBALDH1A1FTO
SCHEMBL12816149	0.81	RXRA (0.45)	RXRARXRBALDH1A1TSHRFTO
SCHEMBL12817953	0.81	MEN1 (0.42)	RXRARXRBALDH1A1TSHRFTO
SCHEMBL12815975	0.81	ACHE (0.37)	RXRARXRBALDH1A1TSHRFTO
SCHEMBL28208954	0.78	ALDH1A1 (0.50)	RXRARXRBALDH1A1TSHRNOTUM
SCHEMBL2531545	0.74	ALDH1A1 (0.53)	RXRARXRBALDH1A1TSHRNOTUM
SCHEMBL12816700	0.73	ALDH1A1 (0.32)	ALDH1A1TSHRNOTUM
SCHEMBL15410092	0.73	ALDH1A1 (0.32)	ALDH1A1TSHRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012133935-A1	METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (3)	SUMITOMO CHEMICAL COMPANY, LIMITED (JP)	2012-10-04	—	—	WO	disclosed