Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12816710 | 0.85 | PTPN5 (0.33) | BACE1CYP17A1 | |
| Hydrochloric Acid SCHEMBL10320191 | 0.79 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL12815877 | 0.79 | HAO2 (0.35) | BACE1NR3C1HAO2CYP3A4AGXT | |
| Hydrochloric Acid SCHEMBL15408955 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL10317587 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL12817774 | 0.75 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11897224 | 0.75 | KDM4E (0.30) | CYP3A4TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12815869 | 0.75 | NPC1 (0.33) | CYP3A4NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12817686 | 0.75 | ACHE (0.38) | BACE1CYP3A4 | |
| Hydrochloric Acid SCHEMBL12821793 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133935-A1 | METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (3) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |