SCHEMBL12816458

SCHEMBL12816458

Fc1ccccc1-c1[c]cccc1-c1ccccc1F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
IDO1 P14902 1/20 0.33
NPC1 O15118 3/20 0.32
DCUN1D1 Q96GG9 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PTPRC P08575 1/20 0.32
PTPN1 P18031 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MPL P40238 1/20 0.32
CCNE2 O96020 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
PKM P14618 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434023 0.89 NOTUM (0.35) NOTUMKDM4EALDH1A1IDO1NPC1
SCHEMBL6298885 0.82 ALDH1A1 (0.34) NOTUMKDM4EALDH1A1IDO1NPC1
SCHEMBL16720271 0.82 MAPT (0.39) NOTUMKDM4EALDH1A1NPC1MEN1
SCHEMBL2012041 0.82 ACHE (0.46) NOTUMALDH1A1NPC1MEN1KMT2A
SCHEMBL434625 0.82 KCNN4 (0.36) NOTUMIDO1MEN1KMT2A
SCHEMBL6304527 0.82 KCNN4 (0.34) NOTUMKDM4EALDH1A1IDO1NPC1
SCHEMBL434572 0.80 NOTUM (0.35) NOTUMKDM4EALDH1A1IDO1NPC1
SCHEMBL18952590 0.80 APEX1 (0.43) KDM4EALDH1A1NPC1PTPRCPTPN1
SCHEMBL12815748 0.79 CCNE2 (0.35) CCNE2CCNE1CDK2
SCHEMBL2437985 0.79 HSD11B1 (0.38) NOTUMALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937195-B2 Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-20 US disclosed
EP-2691406-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) Sumitomo Chemical Company, Limited (JP) 2014-02-05 EP disclosed
US-20140018564-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed
WO-2012133924-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed
WO-2012133935-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (3) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed