Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720155 | 0.85 | CES2 (0.33) | MAPTHPGDSMN1; SMN2POLBKDM4E | |
| SCHEMBL434023 | 0.84 | NOTUM (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL2373478 | 0.84 | SMN1; SMN2 (0.46) | MAPTHPGDSMN1; SMN2POLBKDM4E | |
| SCHEMBL12816458 | 0.82 | NOTUM (0.34) | MAPTSMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL16720359 | 0.80 | ALDH1A1 (0.40) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16720251 | 0.78 | CA2 (0.35) | MAPTHPGDSMN1; SMN2POLBKDM4E | |
| SCHEMBL6304527 | 0.77 | KCNN4 (0.34) | MAPTKDM4EALDH1A1NPC1L3MBTL1 | |
| SCHEMBL434625 | 0.77 | KCNN4 (0.36) | LMNATDP1MEN1KMT2ANOTUM | |
| SCHEMBL6298885 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2KDM4EALDH1A1HSD17B10PIK3CA | |
| SCHEMBL9988583 | 0.77 | ALDH1A1 (0.46) | MAPTHPGDSMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |