SCHEMBL12816614

SCHEMBL12816614

Cc1cc([Si](C)(C)C)cc([Si](Cl)(c2ccccc2)c2c(C)cccc2C)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12814677 0.90 CYP1A2 (0.33) MAOAMAOBCYP1A2CYP2A6
SCHEMBL12817003 0.90 CYP1A2 (0.32) CYP1A2CYP2A6
SCHEMBL12817110 0.87 MAPT (0.33) CYP1A2CYP2A6
SCHEMBL12816500 0.87 MAPT (0.33) CYP1A2CYP2A6
SCHEMBL12816189 0.84 CYP1A2 (0.30) CYP1A2CYP2A6
SCHEMBL12815674 0.84 SMN1; SMN2 (0.37) MAOBCYP2A6
SCHEMBL12816487 0.84 RAPGEF4 (0.30)
SCHEMBL1314281 0.83 ACHE (0.39) CYP1A2CYP2A6
SCHEMBL12815593 0.83 MAPT (0.33) CYP1A2CYP2A6
SCHEMBL12815351 0.82 HPGD (0.38) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012133929-A1 METHOD FOR PRODUCING THE TRANSITION METAL ION COMPLEX, CATALYST FOR TRIMERIZATION, AND METHOD FOR PRODUCING 1-HEXENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed