Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12818273 | 0.94 | PGR (0.36) | GCKPGR | |
| SCHEMBL12817726 | 0.86 | HSPD1 (0.38) | GCKPGRALDH1A1MAPTHPGD | |
| SCHEMBL12817667 | 0.84 | PGR (0.39) | GCKPGRMEN1USP2ALDH1A1 | |
| SCHEMBL12819156 | 0.84 | PGR (0.39) | GCKPGRMEN1USP2ALDH1A1 | |
| SCHEMBL12817925 | 0.83 | PGR (0.40) | GCKPGRMEN1USP2ALDH1A1 | |
| SCHEMBL12817929 | 0.83 | PGR (0.40) | GCKPGRMEN1USP2ALDH1A1 | |
| SCHEMBL12818423 | 0.82 | CYP11B1 (0.39) | PGRMEN1ALDH1A1KMT2A | |
| SCHEMBL12818249 | 0.81 | PGR (0.42) | PGR | |
| SCHEMBL12818535 | 0.81 | CYP11B1 (0.37) | GCKPGRMAPT | |
| SCHEMBL12818669 | 0.80 | PKM (0.37) | PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |