Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18677242 | 0.83 | LTA4H (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12304075 | 0.83 | MAPT (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5325398 | 0.81 | MAOA (0.49) | MAPTLTA4HALDH1A1MEN1KMT2A | |
| SCHEMBL5539652 | 0.78 | LTA4H (0.53) | MAPTLTA4HALDH1A1MEN1KMT2A | |
| SCHEMBL27965042 | 0.78 | MAPT (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27968468 | 0.78 | MAPT (0.41) | MAPTLTA4HALDH1A1MEN1KMT2A | |
| SCHEMBL6205484 | 0.77 | TNFRSF1A (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5023959 | 0.77 | LTA4H (0.66) | MAPTLTA4HALDH1A1MEN1KMT2A | |
| SCHEMBL10185913 | 0.75 | GRIN2B (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12819987 | 0.74 | CYP11B1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |