Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | AOC2 | O75106 | 4/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | DAO | P14920 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31467392 | 0.99 | MAOA (0.61) | MAOAAOC2MAOBDAOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31467273 | 0.87 | AOC2 (0.55) | MAOAAOC2MAOBDAOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31467391 | 0.85 | AOC2 (0.52) | MAOAAOC2MAOBDAOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31467363 | 0.85 | AOC2 (0.59) | MAOAAOC2MAOBDAOALDH1A1 | |
| Hydrochloric Acid SCHEMBL31467375 | 0.78 | AOC2 (0.48) | MAOAAOC2MAOBDAOAOC3 | |
| SCHEMBL3505391 | 0.77 | AOC2 (0.68) | MAOAAOC2MAOBDAOSMN1; SMN2 | |
| SCHEMBL24147678 | 0.76 | MAOB (0.51) | MAOAAOC2MAOBDAOAOC3 | |
| SCHEMBL1282142 | 0.75 | AOC2 (0.64) | MAOAAOC2MAOBDAOALDH1A1 | |
| SCHEMBL1282141 | 0.75 | AOC2 (0.64) | MAOAAOC2MAOBDAOALDH1A1 | |
| SCHEMBL25355719 | 0.74 | MAOB (0.69) | MAOAAOC2MAOBDAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2023-08-17 | — | — | US | disclosed |
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2023-08-17 | — | — | US | disclosed |
| WO-2021258159-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | PHARMAXIS LTD. (AU) | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257342-A1 | HALOALLYLAMINE DUAL AMINE OXIDASE INHIBITORS | AOC2, AOC3, AOC1 | MAOA 6/4885AOC2 1/4885MAOB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.